The figures

HIV/AIDS:

33.4 million are currently living with HIV/AIDS.
More than 25 million people have died of AIDS worldwide since the first cases were reported in 1981.
In 2008, 2 million people died due to HIV/AIDS, and another 2.7 million were newly infected.
While cases have been reported in all regions of the world, almost all those living with HIV (97%) reside in low- and middle-income countries, particularly in sub-Saharan Africa Source

Malaria:

In 2012, malaria killed an estimated 483,000 children under five years of age. That is 1300 children every day, or one child almost every minute.
Malaria is an entirely preventable and treatable mosquito-borne illness. In 2013, 97 countries had on-going malaria transmission.
An estimated 3.4 billion people are at risk on malaria, of which 1.2 billion are at high risk.
There were an estimated 207 million cases of malaria in 2012 and an estimated 627,000 deaths. 90% of all malaria deaths occur in sub-Saharan Africa, and 77% occur in children under five. Source

Human Trafficking:

Human Trafficking is the acquisition of people using force, deception, or coercion with the intent to exploit.
There is an estimated amount of 2 million children exploited in the commercial sex industry worldwide.
Human trafficking generates approx. $150 billion annually at the expense of humans sold for sex and labor. Source

Hunger:

Nearly 870 million people of the 7.1 billion people in the world, or one in eight, were suffering from chronic undernourishment in 2010-2012. Almost all the hungry people, 852 million, live in developing countries, representing 15 percent of the population of developing countries. There are 16 million people undernourished in developed countries.
Children are the most visible victims of undernutrition. Children who are poorly nourished suffer up to 160 days of illness each year. Poor nutrition plays a role in at least half of the 10.9 million child deaths each year–five million deaths. Source

Water:

In Africa alone, people spend 40 billion hours every year just walking for water.
1 billion people do not have access to safe water supply sources.
About 1.8 million people die every year due to preventable diarrheal diseases. Most of them are children under the age of five.
Diseases from unsafe water and lack of basic sanitation kill more people every year than all forms of violence, including war. Source

Sweatshops:

In developing countries, an estimated 250 million children ages 5-14 are forced to work.
Because women make up 85-90 percent of sweatshop workers, employers force them to take birth control and routine pregnancy tests to avoid supporting maternity leave or providing appropriate health benefits.
Men and women alike are subjected to verbal, physical, and sexual abuse in factories from their managers and supervisors. They are sometimes trapped in the factory and forced to work overnight or across multiple shifts.
According to the National Labor Committee, women sewing NBA jerseys make 24 cents per garment that will eventually sell for $140. Source

Child soldiers:

There are an estimated 250,000 child soldiers in the world today.
As part of their recruitment, children are sometimes forced to kill or maim a family member – thus breaking the bonds with their community and making it difficult for them to return home.
It is estimated that 40% of all child soldiers are girls. Source

Persecuted Church:

About 170,000 Christians are martyred for their faith each year (over 400 per day.)
Christians are persecuted in 131 of the world’s 193 countries.
Currently over 200 million Christians are being persecuted worldwide. Source

Orphans:

It is estimated there are between 153 million world wide, who have lost either 1 or both parents.
13 million have lost both parents.
Every day 5,760 more children become orphans.
10% – 15% of these children commit suicide before they reach age eighteen.
60% of the girls become prostitutes and 70% of the boys become hardened criminals. Source

Education of girls

When a girl in the developing world receives seven years of education,she marries four years later and has 2.2 fewer children.
In sub-Saharan Africa, fewer than one in five girls makes it to secondary school. Source

One child policy:

Since the 1 child policy began in China, 37 million girls have been aborted.
In 2012, there were over 18 million more boys than girls under the age of 15 in China.
In 2012, the national government estimated that China has 40 million more males than females.
After their first child, most mothers must receive an IUD implantation and have quarterly check-ups to ensure the IUD remains in place.
According to the Chinese government, over 336 million forced and coerced abortions have taken place under the One-Child Policy, the majority being girls due to a cultural preference for boys. Source

Extreme poverty:

2.4 billion people live on less than $2/day (USD), and roughly 1.2 billion people live on less than $1.25/day (USD) Source

Refugees:

Displaced People:

Homelessness:

Unreached people:

Disabilities:

650 million people live with a disability
Unemployment among the persons with disabilities is as high as 80% in some countries Source

Child brides:

One third of the world’s girls are married before the age of 18 and 1 in 9 are married before the age of 15
Girls living in poor households are almost twice as likely to marry before 18 than girls in higher income households
Girls younger than 15 are five times more likely to die in childbirth than women in their 20s. Pregnancy is the leading cause of death worldwide for girls ages 15 to 19 Source